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One of the attempts to approach the understanding of the mechanisms of aging is the hypothesis of programmed aging that we develop in the last few years. Still II Mechnikov considered old age as a giant atrophy”The body’s body. Along with the death of cells of the brain, liver, muscles and other organs, during aging, the cells of connective tissue multiply, activate their activity, which is expressed in the production of intercellular substance, from which various connective tissue fibers are formed. Now the conclusion is clear to many: to find mechanisms of aging of multicellular organisms is to find out the causes that cause the damage and death of some cells and the multiplication and activation of others. The whole amount of known data indicates that the activation of connective tissue in old age is somehow connected with the death of functionally important cells of tissues or organs. Consequently, the main issue of gerontology, from our point of view, Cell death , as is well known, occurs at all stages of the ontogenesis of the individual: both in embryogenesis, in reproductive and post-production periods. Aging is the consequence of this cell death. If at the initial stage (in embryogenesis) the death of cells provides a normal course of morphogenesis, then in the postnatal period, when the morphogenesis decays, the death and damage of cells and the interstitial and interorganic interrelations arising from these phenomena cause that weakening of the organism’s viability, which we call aging.

Post Author: admin